Math Biology Seminar: Models and manipulations: Min oscillations inside an E. coli bacterium

Subcellular oscillations of Min proteins within individual cells of E. coli serve to localize division to midcell. While significant progress has been made to understand the Min oscillation both experimentally and in modeling, I will present three outstanding Min mysteries. I will also present our ongoing work to develop generic submodels of the Min oscillation, and to systematically manipulate the Min oscillation experimentally. In particular, we find that the period of the Min oscillation responds dramatically to temperature and to the concentration of extracellular multivalent cations (including antimicrobial peptides).