Math Biology Seminar: Claire Guerrier

How Xenopus brain neurons can improve or shift their encoding in response to experience? The present work is in collaboration with the Haas lab, which recent innovations in two-photon calcium imaging allows the simultaneous sampling of all visual-evoked synaptic input and firing output of individual neurons before, during and after visual training that enhanced evoked responses.

In order to analyze and interpret these data, I am currently building several models for calcium dynamics in neurons. The purpose being to understand the origins of calcium transients, the integration of synaptic input to action potential output underlying encoding, and finally how neurons alter these properties to improve encoding with experience.