Math Biology Seminar: Catherine Byrne

Epstein-Barr virus (EBV) is a ubiquitous infection worldwide and is associated with the development of several kinds of cancers. Rates of EBV replication and disease are higher in individuals who are co-infected with HIV-1; however, the causes of this remain unknown. Here, we developed a mathematical model to describe the dynamics of EBV infection within the tonsils and analyzed oral EBV shedding data in a cohort of adults from Uganda to predict the role of HIV-1 in determining infection severity.