Gautam I. Menon

DNA in the form of chromosomes is packaged by histones, proteins that help to compact the approximately 2m of DNA in our nuclei into a nuclear space of a few microns in extent. The combination of DNA, and the proteins and RNA which bind to it, is...

Cells provide highly crowded environments for the processes governing life to play out. We have been exploring some contexts, involving the transport of vesicle-encapsulated material down axons in nerve cells, where crowding appears to be crucial to...

Changes in cell-substrate adhesion are believed to signal the onset of cancer metastasis, but such changes must be quantified against background levels of intrinsic heterogeneity between cells. Variations in cell-substrate adhesion strengths can be...